LexRx Nurse Practitioners determine candidacy for this smile lines treatment during an in-person assessment and consultation. If appropriate, our injectors will conservatively restore structural integrity and volume to the nasolabial folds to help improve creasing / shadowing without distorting an individual’s natural anatomy. Injections can be done with both needle and/or cannula, and are typically mid-dermis. With a collaborative treatment plan and optimal correction, results can last 6-12 months.